
“I think it’s really important that people keep signing up to these type of trials to push research forward.”
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is looking at magnetic resonance spectroscopy (MRS) to measure how cancer treatment is working. MRS scans are a type of MRI scan. Cancer Research UK supports this study.
To tell how well a treatment is working doctors often look for substances in the body (biomarkers) that they can measure. They usually do this by taking blood or tissue samples.
In this study the researchers want to see if they can use a biomarker, called lactate. Lactate is a substance that is made by normal body cells and cancer cells. MRS scans can identify lactate in cells.
We know from research that many cancers make large amounts of lactate. We also know that many cancer drugs can change the amount of lactate that cancer cells make. The researchers think they may be able to tell how well a treatment is working by looking for changes to the amount of lactate using MRS scans.
The aims of this study are to
Please note - You are unlikely to get any direct benefit from joining this study, but the results may help to improve the way cancer is treated in the future.
You may be able to enter this study if you are in one of the following groups
You cannot enter this study if you are not able to have an MRI scan. For example, because you have a pacemaker or other metal in your body, you cannot cope with being in small spaces or you can’t lie flat for at least 40 minutes.
This study will recruit a total of 90 people. There are 4 groups
If you have lymphoma, you have a scan before starting treatment and a week after starting treatment.
If you have bowel cancer, you have 2 scans in the week before starting treatment and another 2 scans after treatment.
If you are taking part in a phase 1 trial, you have 2 scans in the week before starting treatment and another 2 scans after treatment.
Each scan takes about 40 minutes.
You have your scans at the MRI department of the Royal Marsden Hospital, Sutton.
There are no side effects from taking part in this study.
We have more information about MRI scans.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Nandita Desouza
Cancer Research UK
Institute of Cancer Research (ICR)
NIHR Clinical Research Network: Cancer
The Royal Marsden NHS Foundation Trust
National Institute for Health Research Clinical Research Facility in Imaging
Freephone 0808 800 4040
“I think it’s really important that people keep signing up to these type of trials to push research forward.”