
Last year in the UK over 60,000 cancer patients enrolled on clinical trials aimed at improving cancer treatments and making them available to all.
This study looked at using a mobile phone programme to check on people’s side effects when they were taking a chemotherapy drug called capecitabine. The researchers hoped this would help doctors manage side effects better, and decide when they could safely increase someone’s dose to help treat their cancer.
Researchers always need to weigh up the benefits of treatment against how it affects people’s . Doctors want to be able to give the highest dose of capecitabine that they can, without causing too many bad side effects.
The researchers in this trial wanted to see if there was a way of safely increasing the dose of capecitabine for people who were doing well. They looked at people who were taking capecitabine for either breast cancer or bowel cancer that had spread to another part of the body. They checked to see how they were getting on with text messages twice a day. From this the doctor could change their dose either by text or at the clinic, depending on the side effects the person reported.
This study aimed to develop a system to manage side effects and adjust doses so that each person could have the highest dose possible to treat their cancer.
The researchers found that it was possible to safely change the dose by keeping a check on the side effects of capecitabine using a mobile phone application. They say that the instant side effect record from the application might help people to have the best dose possible to treat their cancer.
26 people took part in this small study. They were each given a mobile phone with the application loaded onto it. Everybody completed a side effect questionnaire, temperature and dose diary twice a day, using the application. The phone sent this information to a secure central database.
The computer analysed all the information each time someone filled in their diary and if necessary,
The researchers looked at all the information they had collected. They found that
The study team concluded that it is possible to use a mobile phone application to check on treatment side effects. And to change people’s capecitabine dose so they can have the best dose possible to treat their cancer.
We have based this summary on information from the team who ran the trial. The information they sent us has been reviewed by independent specialists () and published in a medical journal. The figures we quote above were provided by the trial team. We have not analysed the data ourselves.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Andrew Weaver
NIHR Oxford Biomedical Research Centre
Oncology Clinical Trials Office (OCTO)
University of Oxford
Vodafone UK Foundation
Freephone 0808 800 4040
Last year in the UK over 60,000 cancer patients enrolled on clinical trials aimed at improving cancer treatments and making them available to all.