Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A study looking at the genetics of papillary kidney cancer (GPKC study)
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is looking at the genetics of one type of kidney cancer. The researchers are looking for genes that may increase the risk of a type of kidney cancer called papillary renal cell cancer. The study is supported by Cancer Research UK.
The researchers will look at blood samples and samples of tumours from people who have had papillary renal cell cancer to try to identify genes that could affect the risk of getting the disease.
Please note - you won’t get any direct benefit from taking part in this study, and it won’t affect any treatment you have. But may it help people in the future.
Who can enter
If you have had papillary renal cell cancer and are at least 18 years old, your specialist may ask you to join the study, or you may receive a letter.
If you agree to take part in the study, you fill out a questionnaire and give a small blood sample.
The questionnaire asks about your medical history and details of anybody else in your family who has had kidney cancer.
The researchers will use your blood sample to study your DNA to try to find genes that could affect the risk of papillary kidney cancer.
If you have had surgery to remove kidney cancer, the researchers may ask your permission to get a sample of the cancer from the hospital where you had your operation.
The study team may ask you to forward a letter about the study to any of your relatives who have also had papillary renal cell cancer. If they are interested in taking part, they can then contact the study team by sending back the reply slip included with the letter. The study team will not approach your relatives without their permission.
If you agree to join the study during a hospital visit, you can have a blood test at the same time.
If you agree to join the study after receiving a letter, you can make an appointment at your GP practice to have the blood test.
You may have some discomfort or bruising in the area where the blood sample is taken. There are no other side effects associated with the study.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Ian Tomlinson
Cancer Research UK
Experimental Cancer Medicine Centre (ECMC)
NIHR Clinical Research Network: Cancer
University of Birmingham