Last year in the UK over 60,000 cancer patients enrolled on clinical trials aimed at improving cancer treatments and making them available to all.
A study looking at a diet and exercise programme after treatment for womb cancer (DEUS)
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This study looked at whether it would be possible to run a larger trial looking at diet and exercise for women who have had womb cancer treatment. It was for women who have no sign of their cancer after treatment.
More about this trial
An active lifestyle and healthy diet can help improve health and quality of life. Researchers want to see if they can help women change their eating habits and improve their levels of physical activity after treatment for womb cancer. They hope that improving diet and increasing physical activity will help these women to improve their quality of life.
This study was done to see if it would be possible to run a larger trial looking at improving quality of life after womb cancer treatment. This is called a pilot study.
Some women in this study continued with their usual activity and diet. Other women attended group sessions to help increase their physical activity and improve their diet.
The main aims of this study were to find out how many women would:
- be willing to join the study
- attend the group sessions
- complete all the assessments with a researcher
Summary of results
This study showed that women are willing to take part in and complete a trial looking at improving diet and increasing physical activity.
The research team identified 296 women with womb cancer who would be eligible to join this study. And 60 of these women (20%) agreed to join. The main reasons women gave for not taking part were that it wasn’t convenient, or that travel to the sessions would be difficult.
The women who took part had all been diagnosed within the last 3 years. Most had stage 1 womb cancer and all had no signs of their cancer after treatment.
They were put into one of two groups at random. Of the 60 women who joined the study:
- 6 women were not able to take part in the study
- 26 women took part in the new Shape Up following cancer treatment programme
- 28 women had follow up care as usual
The women who did the Shape Up following cancer treatment programme had group sessions once a week for 8 weeks. Each session lasted about an hour and a half. The sessions covered things such as healthy eating and physical activity.
Everyone taking part met with a researcher at the beginning, the middle and the end of the study. The researcher did various assessments including weight, blood pressure and grip strength. The results of these assessments haven’t been published yet. We plan to update this page once they are available.
The research team looked at how many women attended the group sessions and assessments. They found that:
- 24 out of 28 women (92%) who had follow up care as usual completed all the assessments
- 25 out of 26 women (96%) who did the Shape Up following cancer treatment programme completed all the assessments
- 20 out of 26 women (77%) went to the Shape Up following cancer treatment programme group sessions
They also asked the women what they thought about the sessions. The feedback was very positive, with all the women saying that they liked the group session format and length of the sessions.
The research team concluded that a larger trial looking at exercise and diet after treatment for womb cancer would be possible. They suggest thinking about a combination of group sessions and online activities to help increase the number of women willing to take part.
We have based this summary on information from the research team. The information they sent us has been reviewed by independent specialists (
How to join a clinical trial
Dr Anne Lanceley
Barts Health NHS Trust
Experimental Cancer Medicine Centre (ECMC)
NIHR University College London Hospitals Biomedical Research Centre
University College London (UCL)