A study developing a set of questions to help doctors identify problems after pelvic radiotherapy (DESIGNER)

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Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Anal cancer
Bladder cancer
Bowel (colorectal) cancer
Cervical cancer
Ovarian cancer
Prostate cancer
Rectal cancer
Vaginal cancer
Womb (uterine or endometrial) cancer





This study is developing a brief set of questions that will help doctors to identify people who have tummy or bowel problems following radiotherapy treatment for cancer.

If you have radiotherapy to the area between your hips (the pelvis Open a glossary item), you may have some long term side effects such as diarrhoea or pain.

Although pelvic radiotherapy side effects are quite common, doctors don’t always pick up the symptoms. In this study, researchers are developing a brief set of questions to help doctors identify the problems, so that they can refer people to a specialist for help controlling these symptoms. They call this a screening tool.

The study team will ask people who have had problems after radiotherapy to fill out the screening tool they are developing. They will then ask them about any possible problems they can see with using the tool. Their answers will help the researchers to finalise the tool ready to be used by doctors.

Taking part in this study will not change your treatment in any way. The researchers hope that the results will help doctors to identify people who may need help with symptoms after pelvic radiotherapy.

Who can enter

You may be able to enter this study if you

  • Had radiotherapy to your pelvis Open a glossary item more than 3 months ago as part of treatment to cure cancer
  • Don’t have any signs of cancer now
  • Have developed bowel or tummy problems since having radiotherapy
  • Are at least 16 years old
  • Are able to understand the screening tool and talk about it in an interview

You cannot enter this study if you

  • Are having specialist treatment for any other disease affecting your digestive system Open a glossary item such as inflammatory bowel disease or coeliac disease

Trial design

The study will recruit 10 to 15 people. If you agree to take part, you complete the screening tool that the study team are developing. A researcher will then interview you and ask about any possible problems with the wording and the instructions for using the tool.

They will make notes and with your permission, they will make an audio recording of the interview.

All the information you give is confidential Open a glossary item and it will not be possible to identify you in any results of the study.

Hospital visits

The interview will take place either at hospital or in your home, depending on which is most convenient for you.

Filling in the screening tool and having the interview will take between half an hour and an hour.

Side effects

There are no side effects from taking part in this study. If the researcher feels that you mention something that needs to be discussed with your medical team, they will ask your permission to talk to your doctor or nurse.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr John Green

Supported by

Cardiff University
National Institute for Health Research Cancer Research Network (NCRN)

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:

Oracle 10987

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Cara took part in a clinical trial

A picture of Cara

"I am glad that taking part in a trial might help others on their own cancer journey.”

Last reviewed:

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