A trial looking at ofatumumab for mantle cell lymphoma

This trial looked at ofatumumab for mantle cell lymphoma that had come back after treatment.

Mantle cell lymphoma is a rare type of non Hodgkin lymphoma (NHL). Doctors often treat mantle cell lymphoma with chemotherapy, radiotherapy and biological therapy. But it can be difficult to treat, or can come back after treatment.

Ofatumumab (Arzerra) is a type of biological therapy called a monoclonal antibody. Monoclonal antibodies can seek out cancer cells by looking for particular proteins.

Ofatumumab has been used to treat other types of cancer, and doctors hoped it would be useful for treating mantle cell lymphoma.

The aim of this trial was to see how well ofatumumab works for mantle cell lymphoma.