A study to understand more about an eye cancer called uveal melanoma (Liverpool Ocular Oncology Biobank)
Cancer type:
Status:
Phase:
This study is gathering information from blood and tissue samples, which may help to predict outlook (
) and identify new treatments for people with uveal melanoma.
More about this trial
Uveal melanoma is a type of eye cancer. The uvea is the middle tissue layer of the eyeball.
Scientists want to identify which and proteins behave abnormally in this disease. By studying blood and tissue samples from people having surgery to remove uveal melanoma, they hope to
- Find features of uveal melanoma that would help them tell whether the cancer was likely to spread
- Develop a blood test which would show if a cancer had spread when this had been missed by other tests
- Find possible targets in the cancer tissue that may respond to current treatment, or give clues to help design new treatments
Who can enter
You can enter this study if
- Your doctor thinks you may have a type of eye cancer affecting the tissues of the middle layer of your eye (uveal melanoma)
- You are due to have surgery to the affected eye
- You are between 18 and 90 years of age
Trial design
The study has already recruited more than 2000 people and will continue to recuit people with a rare eye cancer in order to support ongoing research.
People taking part may give blood samples for the study. They also give the study team permission to use some of the eye tissue removed during surgery for research.
These samples are being used in research studies and projects conducted by the University of Liverpool, Liverpool Ocular Oncology Research Group (LOORG) and people they work with (collaborators) in this country and abroad.
Hospital visits
You will give your study blood samples at your routine hospital appointments. So you do not have to make any extra visits to hospital to take part in this study.
Side effects
As there are no additional treatments in this study outside of the normal care that you receive, there are no side effects.
Location
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Chief Investigator
Professor Sarah Coupland
Supported by
Aintree University Hospitals NHS Foundation Trust
Clatterbridge Cancer Centre NHS Foundation Trust
Fight for Sight (British Eye Research Foundation)
North West Cancer Research
Pathological Society
Royal Liverpool and Broadgreen Hospital Charitable Funds
Royal Liverpool and Broadgreen University Hospital NHS Trust
University of Liverpool
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
