A study looking for biomarkers of ovarian cancer
Cancer type:
Status:
Phase:
In this study researchers are looking at the blood and tissue samples of women who are having their ovaries removed by surgery. It is open to women who have ovarian cancer and non cancerous (
) conditions.
More about this trial
Researchers will look for substances () in these samples. They will compare the level of the substances in the samples of both groups of women.
The main aim is to identify biomarkers that might help doctors diagnose ovarian cancer earlier.
Who can enter
The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
You may be able to join this study if you are at least 18 years old and are in one of the following situations. You
- are having surgery to remove your ovaries
- are having a sample of tissue (
biopsy ) taken from your ovaries or omentum because you might have cancer - have
Lynch syndrome and are having both your ovaries removed to reduce the risk of having cancer - are having your womb removed (
hysterectomy) or your ovaries removed (oophorectomy) because you have a non cancerous (benign) condition such as menorrhagia or fibroids and you have had an ultrasound scan that shows your ovaries are normal
You cannot join this study if any of these apply. You
- have an infection
- are unable to understand English well enough or English isn’t your first language
Trial design
The researchers need 224 people with ovarian cancer and 224 people who have a benign (non cancerous) condition to join.
The researcher will
- ask you a few questions about your health
- take a blood sample
- ask for a sample of your ovary tissue removed when you have surgery
The team use the samples to look for substances (biomarkers). These biomarkers might help doctors diagnose ovarian cancer earlier. And also tell them if treatment is working.
Hospital visits
There are no extra hospital visits.
Side effects
We have information about surgery to remove ovarian cancer.
Location
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Chief Investigator
Dr Lavinia Margarit
Supported by
Abertawe Bro Morgannwg University Health Board
Cwm Taf Morgannwg University Health Board
NIHR Clinical Research Network: Cancer
St David's Medical Foundation
Tenovus
Welsh Government
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
