Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A trial looking at gemcitabine and cisplatin for advanced bladder cancer
This trial looked at gemcitabine and cisplatin chemotherapy for bladder cancer that had come back after treatment or spread to another part of the body.
Cisplatin was already being used for advanced bladder cancer, but it does cause side effects. Gemcitabine was a newer drug and appeared to cause fewer side effects.
The aims of the trial were to find out
- The best dose of gemcitabine and cisplatin to use
- More about the side effects
- How well this combination worked for advanced bladder cancer
Summary of results
The research team found that the combination of gemcitabine and cisplatin chemotherapy is useful for treating advanced bladder cancer.
This trial recruited 32 patients aged 41 to 79 with advanced bladder cancer.
- In 4 people the cancer went away - researchers call this ‘
- In 17 people the cancer slowed or stopped growing - researchers call this ‘
- In 6 people the cancer remained the same - researchers call this ‘
- 1 person’s cancer continued to grow
- They did not have results for 4 people
The most common side effect was a drop in blood cell counts.
We have based this summary on information from the team who ran the trial. The information they sent us has been reviewed by independent specialists (
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Nick James
University of Birmingham
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040