A trial looking at a vaccine to treat children with a type of brain tumour called a high grade glioma

This trial was for children between the ages of 3 and 18. We use the term ‘you’ in this summary, but if you are a parent we are referring to your child.

If you have a type of brain tumour called a glioma, and the tumour cells are fast growing (high grade), your treatment may include

• surgery
• radiotherapy
• chemotherapy.

In this trial, doctors wanted to see if adding a vaccine to treatment boosted the immune system to kill more brain tumour cells.

The aims of this trial included

• Seeing how possible it is to make and give these vaccines to children
• Learning more about the safety of the vaccines
• Finding out whether adding this vaccine to standard treatment  helps stimulate the immune system