A trial to see if vaccines can stimulate the immune system in healthy volunteers

This trial was done to find out if vaccines can increase the immune response to certain proteins in the body. And if that can affect how well stem cell transplants work.

The first step was to find out what happens in people who don’t have cancer (healthy volunteers). Researchers then hope to give these vaccines to people who are going to donate their stem cells to people with leukaemia or lymphoma.

The trial was open for people to join between 2012 and 2017. The team published the results in 2021.