“I think it’s really important that people keep signing up to these type of trials to push research forward.”
A trial to see if there is a link between the enzyme thymidylate synthase and how people respond to treatment for non small cell lung cancer (The TS Study)
This study tried to find out if a substance produced in the body called thymidylate synthase affects how people respond to chemotherapy for non small cell lung cancer (NSCLC).
More about this trial
Doctors often use chemotherapy to treat NSCLC. Pemetrexed and cisplatin are drugs that may be used.
Thymidylate synthase (TS) is a substance that the body produces naturally. Cancer cells need TS to be able to copy their DNA before they divide into 2 new cells.
Researchers think that treatment for NSCLC may work better in people who have low levels of TS in their body. But they don’t know this for sure yet. So in this trial, they measured the TS levels of everybody having treatment.
The aim of the trial was to see if there is a link between how much TS people produce and how well they respond to treatment with pemetrexed and cisplatin for non small cell lung cancer.
Summary of results
Despite attempting to contact the trial team, we have not been able to have the results for this trial checked.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Mayukh Das
Eli Lilly and Company Limited
Experimental Cancer Medicine Centre (ECMC)