A trial to find out how well gemcitabine and oxaliplatin work for children and young people with cancer (CCLG NAG 2007 01)

This trial looked at the chemotherapy drugs gemcitabine and oxaliplatin, to find out how well they worked for children with solid tumours, and to understand more about their side effects. The trial recruited children and young people whose solid tumour had continued to grow or came back despite treatment.

This trial was for children and young people up to and including the age of 20. We use the term ‘you’ in this summary, but of course if you are a parent, we are referring to your child.

Gemcitabine is used to treat many different types of cancer affecting adults. We know from research that it might be a useful treatment for children.

Oxaliplatin is also used to treat adults with cancer, and was being looked at as a possible treatment for children. Doctors thought that gemcitabine and oxaliplatin may work better if your child had them together.

The aims of this trial were to find out how well this combination of drugs worked and what the side effects were.