A trial to find genes that may increase testicular cancer risk - The UK genetics of testicular cancer study
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
Cancer type:
Status:
Phase:
This study is trying to find out more about the causes of testicular cancer and to identify genes that may be important in the development of this disease.
More about this trial
The risk factors for testicular cancer include having a family history. Research has shown that genetic factors may affect your risk of testicular cancer. But it is rare for more than one person in a family to have testicular cancer.
In this study, the researchers will look at the genes of a large number of men who have had testicular cancer. They will find out more information about their family history and may also look at the genes of the men’s parents.
The aim of the study is to identify genes that could increase the risk of testicular cancer.
Who can enter
You can enter this trial if you have
- Had testicular cancer
- Finished your treatment for testicular cancer
You cannot enter this trial if you are still having treatment for testicular cancer.
Trial design
This trial will recruit 10,000 men who have had treatment for testicular cancer. When you go to see your doctors for a follow up appointment, they may ask you if you would be interested in taking part in the trial. Or, you may receive a letter from your hospital, asking you to take part.
If you are not asked to take part in this study but think you would be eligible, you can also refer yourself. You can do this by contacting the research team.
If you agree to take part, you will be asked to complete a questionnaire about your medical history and family history. Nobody in your family will be contacted without your permission.
You will be asked to give a small sample of blood. You may give this at your GP surgery or hospital, depending on how your local services are arranged. The DNA from your blood sample will be safely stored and only used in this study. The researchers will look at the DNA to try and find genes that may increase the risk of developing testicular cancer. The DNA samples are taken for the purpose of this study only.
The researchers will ask your permission to get a sample of tissue taken in your original operation for testicular cancer. This tissue sample will also only be used for the purpose of this study. Researchers will also ask for permission to look at your medical records.
Hospital visits
Taking part in this study does not involve any extra visits to your hospital, apart from having the blood test.
Side effects
You may have some bruising in the area where the blood sample is taken. There are no other side effects associated with taking part in this study.
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Chief Investigator
Dr Clare Turnbull
Supported by
Cancer Research UK
Experimental Cancer Medicine Centre (ECMC)
Institute of Cancer Research (ICR)
Movember Foundation
NIHR Clinical Research Network: Cancer
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
