Your doctor and nurse will monitor you closely for any side effects. Let your doctor or nurse know as soon as possible if:
- you have severe side effects
- your side effects aren’t getting any better
- your side effects are getting worse
You might have a reaction when you have RO6874281 or atezolizumab. It can happen during, soon after or within 24 hours of having treatment. It usually happens when you first have them. Some of the symptoms can include:
- a high temperature (fever), shivering or chills
- feeling or being sick
- high or low blood pressure
- changes to your heart beat
- breathing difficulties
You have medication before starting treatment to prevent a reaction. You are monitored closely during and for a while after treatment.
Tell your nurse if you have any of the above symptoms during treatment. After treatment contact your healthcare advice line if you have any of the above.
RO6872481 is a new drug and there might be side effects we don’t know about yet. The side effects reported so far include:
- high temperature (fever)
- capillary leak syndrome – if you feel faint, sick and have swollen ankles or legs contact your doctor or the health care advice line straight away
- changes to the way the heart works
These treatments affect the immune system. This may cause inflammation in different parts of the body which can cause serious side effects. They could happen during treatment, or some months after treatment has finished. In some people, these side effects could be life threatening.
Your doctor or a member of the trial team will talk to you about the possible side effects of RO6874281 and atezolizumab before you agree to take part.