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A trial of olaparib for ovarian cancer that has come back (MOLTO)

Overview

Cancer types:

Ovarian cancer

Status:

Results

Phase:

Phase 2

Details

This trial looked at a second course of olaparib for women with ovarian cancer that had come back after having had platinum chemotherapy and olaparib. It was for women who had a gene change () in or .

It was open to women whose ovarian cancer is one of the following:

  • epithelial ovarian cancer

  • fallopian tube cancer

  • primary peritoneal cancer

These cancers are treated in the same way, so when we use the term ovarian cancer in this summary, we are referring to all 3.

The trial was open for people to join between 2017 and 2019. The team published the results in 2023.

Recruitment start: 26 May 2017

Recruitment end: 9 September 2019

How to join

Please note: In order to you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Gordon Jayson

Supported by

AstraZeneca

The Christie NHS Foundation Trust

Manchester Academic Health Science Centre Trials co-ordination unit (MAHSC-CTU)

Last reviewed: 11 Sept 2023

CRUK internal database number: 14574

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