Bowel (colorectal) cancer, Colon cancer, Rectal cancer, Secondary cancers
Results
Phase 3
This trial looked at how well nivolumab worked for bowel cancer that had grown into the tissue around the bowel or spread to another part of the body. This is called locally advanced or advanced bowel cancer.
It was for people with a certain type of bowel cancer called cancer.
People could join the trial between 2019 and 2021. The team first presented early results in September 2022. They published more results in a medical journal in December 2025.
Recruitment start: 28 August 2019
Recruitment end: 6 September 2021
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Gary Middleton
University of Birmingham
Bristol-Myers Squibb
Cancer Research UK
Experimental Cancer Medicine Centre (ECMC)
Last reviewed: 04 Feb 2026
CRUK internal database number: 16343