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A trial of cyclophosphamide and pembrolizumab for kidney cancer (CAPER)

Overview

Cancer types:

Kidney cancer, Secondary cancers

Status:

Results

Phase:

Phase 1

Details

This trial looked at treatment for kidney cancer that had spread to another part of the body and couldn’t be removed with surgery.

It was for people who had already had for their kidney cancer. But the treatment had stopped working.

People could join the trial between 2021 and 2023. The team reported the results in 2024.

Recruitment start: 26 January 2021

Recruitment end: 20 July 2023

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Tom Waddell

Supported by

Merck, Sharp & Dohme

The Christie NHS Foundation Trust

Cancer Research UK Manchester Institute Cancer Biomarker Centre

Liverpool Clinical Trials Centre

Last reviewed: 11 Dec 2025

CRUK internal database number: 16929

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