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A trial of chemotherapy with or without bevacizumab for ovarian cancer, primary peritoneal cancer or fallopian tube cancer (ICON 7)

Overview

Cancer types:

Ovarian cancer

Status:

Results

Phase:

Phase 3

Details

This trial looked at chemotherapy combined with a monoclonal antibody for ovarian cancer, fallopian tube cancer and primary peritoneal cancer.

Doctors usually treat ovarian cancer with surgery and chemotherapy. They often use the chemotherapy drugs carboplatin and paclitaxel (Taxol).

Bevacizumab (Avastin) is a type of biological therapy called a monoclonal antibody. Researchers hoped that giving bevacizumab as well as chemotherapy may be better than chemotherapy alone.

The aim of this trial was to find out if adding bevacizumab to chemotherapy helps stop ovarian cancer coming back after surgery.

Recruitment start: 13 December 2006

Recruitment end: 16 February 2009

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr T Perren

Supported by

Cancer Research UK

Experimental Cancer Medicine Centre (ECMC)

F.Hoffmann-La Roche Ltd (Roche)

Medical Research Council (MRC)

National Institute for Health Research Cancer Research Network (NCRN)

Other information

This is Cancer Research UK trial number CRUKE/05/024.

Last reviewed: 1 August 2016

CRUK internal database number: 716

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