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A trial of cediranib for women with ovarian cancer at risk of bowel obstruction (CEBOC)

Overview

Cancer types:

Ovarian cancer, Secondary cancers

Status:

Results

Phase:

Phase 2

Details

This trial looked at adding a drug called cediranib to paclitaxel chemotherapy for ovarian cancer. The aim was to reduce the risk of developing a blockage in the bowel. This can happen if a cancer spreads from the ovary.

It was for women whose ovarian cancer had come back or continued to grow after . The trial included women who had:

  • epithelial ovarian cancer

  • fallopian tube cancer

  • primary peritoneal cancer

Doctors treat these cancers in the same way. So, when we use the term ovarian cancer in this summary, we are referring to all 3.

The trial was open for people to join between 2018 and 2021. The team published the results in 2024.

Recruitment start: 10 April 2018

Recruitment end: 15 February 2021

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Gordon Jayson

Supported by

AstraZeneca

Centre for Trials Research (Cardiff University)

University of Manchester

Last reviewed: 7 July 2025

CRUK internal database number: 15322

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