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A trial of depatuxizumab mafodotin for glioblastoma that has come back (INTELLANCE 2)

Overview

Cancer types:

Brain (and spinal cord) tumours

Status:

Results

Phase:

Phase 2

Details

This trial looked at depatuxizumab mafodotin (Depatux-M, ABT-414) with or without temozolomide. It was for people with glioblastoma that came back after their first treatment (surgery and or radiotherapy).

It was open to people whose glioblastoma had a larger number of receptors for the protein called epidermal growth factor (EGF).

This trial was open for people to join between 2015 and 2016. The trial team published the results in 2020.

Recruitment start: 30 July 2015

Recruitment end: 30 June 2016

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Paul Mulholland

Supported by

AbbVie

Experimental Cancer Medicine Centre (ECMC)

European Organisation for Research and Treatment of Cancer (EORTC)

Last reviewed: 06 Jan 2022

CRUK internal database number: 13514

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