Cancer Research UK logo.
SearchDonate
  • Search

A trial looking at a new drug called olaparib for leukaemia and mantle cell lymphoma that has stopped responding to treatment (PICLLE)

Overview

Cancer types:

Blood cancers, Chronic leukaemia, Chronic lymphocytic leukaemia (CLL), Leukaemia, Low grade lymphoma, Lymphoma, Non-Hodgkin lymphoma (NHL)

Status:

Results

Phase:

Phase 1/2

Details

The trial team wanted to find the best dose of olaparib to treat leukaemia and lymphoma and if it might help people live longer. It was open to people with:

  • chronic lymphocytic leukaemia (CLL)

  • T-prolymphocytic leukaemia (T-PLL)

  • mantle cell lymphoma

Recruitment start: 13 July 2011

Recruitment end: 23 January 2015

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Guy Pratt

Supported by

AstraZeneca

Bloodwise

Experimental Cancer Medicine Centre (ECMC)

NIHR Clinical Research Network: Cancer

University of Birmingham

Last reviewed: 25 January 2019

CRUK internal database number: 7447

The Dangoor Education logo.

Dangoor Education

About Cancer generously supported by Dangoor Education since 2010. Learn more about Dangoor Education

Patient Information Forum. Trusted Information Creator.
Plain English Campaign award.

Help and support

An icon of a hand shake.

Questions for your doctor

What to ask your doctor about clinical trials.

An icon of two speech bubbles, indicating a conversation.

Cancer chat forum

Meet and chat to other cancer people affected by cancer.

An icon of a landline phone.

Nurse helpline

Questions about cancer? Call freephone 0808 800 40 40 from 9 to 5 - Monday to Friday. Alternatively, you can email us.