A trial looking at drugs called LJM716 and BYL719 for cancer of the food pipe

This trial is looking at 2 new drugs LJM716 and BYL719 for cancer of the food pipe (oesophageal cancer). This trial is for people with oesophageal cancer that has come back after treatment or has spread.

Doctors often use chemotherapy to treat oesophageal cancer. They may use a combination of chemotherapy drugs including a platinum drug. Unfortunately for some people their cancer may not respond to this treatment or may come back afterwards. Doctors are looking for ways to treat these people.

LJM716 is a type of biological therapy called a monoclonal antibody. It seeks out cancer cells by looking for particular proteins.

BYL719 is also a type of biological therapy. It is a cancer growth blocker . It stops signals that cancer cells use to divide and grow.

The researchers think that having LJM716 and BYL719 may help people whose oesophageal cancer has come back after treatment or has spread.