A trial looking at denosumab with chemotherapy for non small cell lung cancer

This trial is looking at a drug called denosumab with chemotherapy for non small cell lung cancer. It is for people with non small cell lung cancer (NSCLC) that has spread to another part of their body.

Doctors can treat NSCLC with chemotherapy. They usually use a platinum drug, such as cisplatin or carboplatin alongside another chemotherapy drug. In this trial, they are looking at adding a drug called denosumab.

Denosumab is a type of biological therapy called a monoclonal antibody. Doctors use it to treat cancer that has spread to the bones or to delay it spreading to the bones.

The researchers want to find out more about how denosumab works in people with NSCLC. They also want to find out about how denosumab works alongside platinum chemotherapy drugs.

The researchers will look at certain substances (biomarkers) in your cancer tissue and blood.

The main aim of this trial is to find out if there is a link between the biomarkers and how well the combination of denosumab and platinum chemotherapy works for NSCLC.