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A trial looking at axitinib for advanced bowel cancer (AXMUS C)

Overview

Cancer types:

Bowel (colorectal) cancer, Colon cancer, Rectal cancer

Status:

Closed

Phase:

Phase 2

Details

This trial is looking at axitinib to treat bowel cancer that has spread to another part of the body (advanced bowel cancer).

Doctors can treat advanced bowel cancer with chemotherapy. But sometimes this doesn’t work and the cancer continues to grow. So they are always looking for new treatments.

Axitinib is a type of targeted cancer treatment called a tyrosine kinase inhibitor. The researchers think that axitinib may help people with advanced bowel cancer that has continued to grow despite having chemotherapy.

As a part of this trial, the researchers also want to look at measuring the blood flow to and from the liver using a new type of called a contrast enhanced ultrasound.

The aims of the trial are to

  • Find out how well axitinib works for people with advanced bowel cancer

  • Learn more about the side effects

  • Test the contrast enhanced ultrasound

Recruitment start: 5 September 2012

Recruitment end: 7 April 2016

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Harpreet Wasan

Supported by

Experimental Cancer Medicine Centre (ECMC)

Imperial College Healthcare NHS Trust

NIHR Clinical Research Network: Cancer

Pfizer

Last reviewed: 06 Apr 2016

CRUK internal database number: 9863

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