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A trial looking at zalutumumab for squamous cell carcinoma of the head and neck

Overview

Cancer types:

Head and neck cancers, Laryngeal cancer, Mouth and oropharyngeal cancer, Nasal and paranasal sinus cancer , Nasopharyngeal cancer, Pharyngeal cancer

Status:

Results

Phase:

Phase 3

Details

This trial looked at zalutumumab for head and neck cancer that continued to grow or came back after chemotherapy with a .

Many head and neck cancers are squamous cell carcinomas. Squamous cells are the flat, skin like cells that cover the inside of the mouth, nose and throat. Carcinoma just means cancer. So squamous cell carcinoma is cancer that starts in these cells.

Zalutumumab is a type of biological therapy called a monoclonal antibody. It seeks out cancer cells by looking for a particular protein.

In this trial, the researchers wanted to find out if zalutumumab stopped or slowed down the growth of squamous cell carcinoma. And to see if it could improve . The aims of the trial were to

  • See if zalutumumab helped people with head and neck cancer

  • Learn more about the side effects

Recruitment start: 1 November 2006

Recruitment end: 10 June 2009

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Prof Christopher Nutting

Supported by

Experimental Cancer Medicine Centre (ECMC)

Genmab

NIHR Clinical Research Network: Cancer

Last reviewed: 30 Jul 2014

CRUK internal database number: 1172

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