A trial looking at treatment for children and teenagers with a primitive neuroectodermal tumour that has come back (PNET-CNS 2000 01)

This trial looked at using high dose chemotherapy and a stem cell transplant for children who had a neuroectodermal tumour that had come back following treatment.

Primitive neuroectodermal tumour (PNET) is a group of brain cancers that mainly occur in children. Doctors treat PNETs in the brain with surgery, radiotherapy and chemotherapy. But sometimes these treatments don’t work very well and the cancer comes back.

This trial was for children and young people up to the age of 21. We use the term 'you' in this summary, but of course if you are a parent, we are referring to your child.

If you have a PNET in the brain that has come back, it is difficult to treat.

The researchers wanted to find out if high dose chemotherapy could improve the treatment for children and young people with PNET in the brain that had come back.