A trial looking at the long term effects of treatment for children and young people who had a germ cell tumour

Cancer type:

Children's cancers





This trial wanted to find out about the long term side effects Open a glossary item of treatment for germ cell tumours. It was for children and young people who had finished treatment at least 5 years previously and who had no sign of their cancer remaining (in remission Open a glossary item).

More about this trial

Germ cells are the cells that produce eggs in females and sperm in males. Rarely these cells become cancerous. Germ cell tumours usually develop in the testicles or ovaries, but can be found in other parts of the body.

Doctors usually treat germ cell tumours with chemotherapy. And some people will have surgery. These treatments generally work very well and most children and young people are cured.

Doctors know that the chemotherapy drugs they use might affect how well certain parts of the body work, such as the lungs and the kidneys. They wanted to understand more about how the cancer and treatment affects quality of life years later.

The aims of this trial were:

  • to find out what the late effects of treatment are 
  • to understand more about how germ cell cancer and its treatment affect quality of life

The doctors wanted to use the information from this trial to improve how they follow up children’s progress after treatment.

Summary of results

The trial team have told us that they found it difficult to find enough children and young people to take part. This means they were not able to publish any results. 

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr. Adam Glaser

Supported by

Children's Cancer and Leukaemia Group (CCLG)
NIHR Clinical Research Network: Cancer

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Katie took part in a new clinical trial

A picture of Katie cycling

"We believed that with the clinical trial, Katie had the best chance of recovery. Without these trials, amazing new treatments may never be found."

Last reviewed:

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