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A trial looking at the drug GSAO in people with advanced cancer (PH1 109)

Overview

Cancer types:

All cancer types

Status:

Results

Phase:

Phase 1

Details

This trial was done to see what happened to a drug called GSAO in the body. This trial was supported by Cancer Research UK.

Cancers need a blood supply to be able to grow. Research in the laboratory had shown that GSAO could help stop the growth of blood vessels (anti angiogenesis) in cancers. Researchers hoped that it would help stop angiogenesis and slow down or stop the growth of cancer in people.

The aims of this trial were to find out

  • The best dose of GSAO to give

  • The effect GSAO has on the body

  • About side effects of GSAO

  • How GSAO affects cancer cells

Recruitment start: 24 January 2008

Recruitment end: 5 March 2012

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Gordon Jayson

Supported by

Cancer Research UK (Centre for Drug Development)

Experimental Cancer Medicine Centre (ECMC)

Other information

This is Cancer Research UK trial number CRUKD/08/041.

Last reviewed: 18 Dec 2013

CRUK internal database number: 680

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