A trial looking at testosterone replacement in young men who have had cancer treatment (TRYMS)

This trial is looking at a gel that contains the male hormone testosterone to see if it helps men who have low levels of testosterone after cancer treatment. The trial is supported by Cancer Research UK.

We know from research that men aged 25 to 50 who have had treatment for cancer may have lower levels of testosterone than other men. A low testosterone level may cause

• An increase in body fat and weight gain

• A reduced sex drive

• A lower sense of general well being

Men who have very low levels of testosterone can have treatment to replace the hormone. But doctors are unsure of the best way to help men who have testosterone levels that are just a bit lower than normal. They call this a borderline low level.

The aim of this study is to see if a gel containing testosterone can help men with borderline low levels of testosterone following cancer treatment. The researchers want to see if it can help reduce body fat, and improve sex drive and general wellbeing.