A trial looking at radiotherapy to the chest after treatment for primary mediastinal large B cell lymphoma (IELSG37)

Overview

Cancer types:

Blood cancers, High grade lymphoma, Lymphoma, Non-Hodgkin lymphoma (NHL)

Status:

Results

Phase:

Phase 3

Details

This trial looked at radiotherapy to the chest after chemotherapy and rituximab for primary mediastinal large B cell lymphoma.

It was for people who had newly diagnosed lymphoma.

People could join between 2012 and 2019. The team published the main key results in 2024.

Recruitment start: 1 July 2012

Recruitment end: 1 August 2019

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Andrew Davies

Supported by

International Extranodal Lymphoma Study Group (IELSG)

Cancer Research UK

Experimental Cancer Medicine Centre (ECMC)

NIHR Clinical Research Network: Cancer

Southampton Clinical Trials Unit

University Hospital Southampton NHS Foundation Trust

Other information

This is Cancer Research UK trial number CRUK/12/040.

Last reviewed: 27 Jul 2026

CRUK internal database number: 10554

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