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A trial looking at radiotherapy after surgery for women over 65 years old with breast cancer (PRIME 2)

Overview

Cancer types:

Breast cancer

Status:

Results

Phase:

Phase 3

Details

This trial looked at whether older women with breast cancer need to have radiotherapy after their surgery.

Women could join the trial between 2003 and 2009. The team first published the results in 2015. They published longer term results in 2023.

Recruitment start: 16 April 2003

Recruitment end: 22 December 2009

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Ian Kunkler

Professor Robin Prescott

Supported by

Chief Scientist Office (CSO)

Experimental Cancer Medicine Centre (ECMC)

Lothian Health Board

NIHR Clinical Research Network: Cancer

Scottish Government

The Breast Cancer Institute

University of Edinburgh

Last reviewed: 30 Jan 2026

CRUK internal database number: 49

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