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A trial looking at PLX3397 for advanced acral and mucosal melanoma (PIANO)

Overview

Cancer types:

Melanoma, Skin cancer

Status:

Closed

Phase:

Phase 2

Details

This trial is looking at a drug called PLX3397 for melanoma that has spread into the surrounding tissues or to another part of the body (advanced melanoma). It is for people who have:

  • 2 unusual types of melanoma called and

  • A gene change () in the melanoma cells called KIT

This trial is supported by Cancer Research UK.

Recruitment start: 28 October 2015

Recruitment end: 28 March 2019

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Paul Lorigan

Supported by

Cancer Research UK

Christie Charitable Funds ‘’Elis for life’’

Central Manchester for Genomic Medicine

Experimental Cancer Medicine Centre (ECMC)

Oxford University Hospitals NHS Trust

The Christie NHS Foundation Trust

The Institute of Cancer Research

University of Manchester

Other information

This is Cancer Research UK trial number CRUK/12/020

Last reviewed: 27 May 2019

CRUK internal database number: 9540

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