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A trial looking at olaparib and radiotherapy for people with glioblastoma (PARADIGM)

Overview

Cancer types:

Brain (and spinal cord) tumours

Status:

Closed

Phase:

Phase 1/2

Details

This trial is looking at olaparib and radiotherapy for people with a type of brain tumour called a glioblastoma who cannot have standard treatment. This includes people over the age of 65 and younger people who have poor health.

Please note, the sub study is open to recruitment. The main study is closed. You can find out about the sub study in the trial design section below.

Cancer Research UK supports this trial.

Recruitment start: 3 March 2015

Recruitment end: 31 March 2025

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Anthony Chalmers

Supported by

AstraZeneca

Cancer Clinical Trials Unit Scotland

Cancer Research UK

Experimental Cancer Medicine Centre (ECMC)

NHS Greater Glasgow & Clyde

NIHR Clinical Research Network: Cancer

University of Glasgow

Other information

This is Cancer Research UK trial number CRUK/13/034.

Last reviewed: 31 Mar 2025

CRUK internal database number: 11764

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