A trial looking at gene therapy for prostate cancer that has continued to grow (GDEPT)

This trial was trying to find out more about a new form of gene therapy called GDEPT for prostate cancer.

The trial was open to men who had prostate cancer that had continued to grow despite treatment.

With this treatment, a specially treated virus is injected directly into the prostate cancer. It carries a gene that can turn a harmless drug called CB1954 into an active anti cancer drug. The harmless drug travels through the bloodstream. When the drug reaches the virus infected cancer cells, it is activated by the gene in the virus and kills the cancer.

The aim of this trial were to find out

• How good the virus was at getting the genes into the prostate gland

• How good the treatment was at killing prostate cancer cells

• What the side effects were