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A trial of chemoradiotherapy with or without cetuximab for oesophageal cancer (SCOPE1)

Overview

Cancer types:

Oesophageal cancer

Status:

Results

Phase:

Phase 2/3

Details

This trial was looking at a drug called cetuximab alongside chemotherapy and radiotherapy for cancer of the food pipe (oesophageal cancer). The trial was supported by Cancer Research UK.

If oesophageal cancer has not spread to other parts of your body, your doctors may suggest that you have a combination of chemotherapy and radiotherapy. This is called chemoradiotherapy.

This trial looked at having cetuximab as well as chemoradiotherapy. Cetuximab is a type of biological therapy, called a monoclonal antibody.

The aims of the trial were to

  • See if adding cetuximab to chemoradiotherapy helped people with oesophageal cancer

  • Learn more about the side effects

Recruitment start: 7 February 2008

Recruitment end: 22 February 2012

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Tom Crosby

Supported by

Cancer Research UK

Department of Health

Health and Care Research Wales

Medical Research Council (MRC)

Merck Serono UK

National Institute for Health Research Cancer Research Network (NCRN)

Velindre NHS Trust

Wales Cancer Trials Unit

Other information

This is Cancer Research UK trial number CRUK/07/003.

Last reviewed: 17 Sept 2013

CRUK internal database number: 797

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