A trial looking at pegylated recombinant human arginase for children and young adults with cancer (PARC)

Overview

Cancer types:

Acute leukaemia, Acute lymphoblastic leukaemia (ALL), Acute myeloid leukaemia (AML), Brain (and spinal cord) tumours, Children's cancers, Leukaemia, Neuroblastoma, Sarcoma, Secondary cancers

Status:

Results

Phase:

Phase 1/2

Details

This trial was for children and young adults with cancer that had come back or continued to grow despite treatment.

It was for people more than 12 months and less than 25 years old, with one of the following cancers:

The trial was supported by Cancer Research UK. It was open for people to join between 2018 and 2022. Unfortunately the trial team weren’t able to get reliable results from the trial.

Recruitment start: 28 August 2018

Recruitment end: 31 July 2022

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Francis Mussai

Supported by

Cancer Research UK

University of Birmingham

Innovative Therapies for Children with Cancer in Europe (ITCC)

European Cancer Organisation Methods in Clinical Research workshop

Last reviewed: 23 Oct 2026

CRUK internal database number: 14953

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