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A trial looking at a new drug called pegylated recombinant human arginase for children and young adults with cancer (PARC)

Overview

Cancer types:

Acute leukaemia, Acute lymphoblastic leukaemia (ALL), Acute myeloid leukaemia (AML), Brain (and spinal cord) tumours, Children's cancers, Leukaemia, Neuroblastoma, Sarcoma, Secondary cancers

Status:

Closed

Phase:

Phase 1/2

Details

This trial is for children and young adults with cancer that has come back or continued to grow despite treatment.

It is for children and young adults with one of the following cancers:

  • a type of leukaemia called acute lymphoblastic leukaemia (ALL) or acute myeloid leukaemia (AML)

  • neuroblastoma

  • sarcoma

  • a type of brain tumour called glioma that usually grows quickly and is likely to spread (high grade glioma)

Everyone taking part needs to be older than 12 months but less than 25 years old. We use the term ‘you’ in this summary, but if you are a parent, we are referring to your child.

Cancer Research UK supports this trial.

Recruitment start: 28 August 2018

Recruitment end: 24 March 2022

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Francis Mussai

Supported by

Cancer Research UK

University of Birmingham

Innovative Therapies for Children with Cancer in Europe (ITCC)

European Cancer Organisation Methods in Clinical Research workshop

Last reviewed: 03 May 2022

CRUK internal database number: 14953

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