All cancer types
Results
Phase 1
This trial looked at a drug called sonidegib (also known as LDE225) for solid tumours that have spread to another part of the body. A solid tumour is any type of cancer apart from or .
Sonidegib is a type of biological therapy. It is a cancer growth blocker. It stops the signals that cancer cells use to divide and grow.
This was the first time that sonidegib was given to patients. The people taking part had different types of advanced cancer that had got worse despite having other treatments. The aims of the trial were to
Find the best dose of sonidegib to give
Learn more about the side effects and what happens to sonidegib in your body
See how well it works for advanced cancer
Recruitment start: 12 March 2009
Recruitment end: 22 September 2011
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Anne Thomas
Experimental Cancer Medicine Centre (ECMC)
Novartis
Last reviewed: 26 Feb 2015
CRUK internal database number: 5890