A trial of ipilimumab after radiotherapy for prostate cancer spread to the bones (CA184043)

This trial looked at a drug called ipilimumab after radiotherapy for prostate cancer that has spread to the bones.

Doctors usually treat prostate cancer that has spread with a chemotherapy drug called docetaxel. But sometimes the cancer stops responding or continues to grow despite having this treatment. So researchers are looking for ways to improve treatment. In this trial, they looked at radiotherapy to the bones followed by a drug called ipilimumab.

Ipilimumab is a type of biological therapy called a monoclonal antibody. It may help the body’s immune system to attack cancer cells.

The aims of this trial were to find out

• How well the combination of radiotherapy and ipilimumab works for prostate cancer that is not responding to other treatments

• More about the side effects