A study to see how often people with advanced cancer have blood clots in their legs (HIDDen)

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

All cancer types





This study is to find out how frequently blood clots (deep vein thrombosis) happen in the legs of people who go into a hospice. This study is for people with an advanced cancer Open a glossary item

More about this trial

Up to 1 in 5 people (20%) with cancer develop a blood clot called a deep vein thrombosis (DVT). Left untreated a DVT could cause serious problems.  

There are national recommendations to prevent DVTs in cancer patients when they go into hospital. But it isn’t known if these recommendations are suitable for people who go into a hospice Open a glossary item

Researchers don’t know if treating a DVT in someone who has advanced cancer will improve any symptoms and change their outlook (prognosis). Or whether the side effects of treating the clot (such as an increased risk of bleeding) would mean that treatment is not appropriate.   

Researchers want to find out how many people with advanced cancer have a DVT when they go into a hospice. And how many develop a DVT while in the hospice.   

They hope this information will eventually: 

  • help doctors and nurses working in hospices know the best way to prevent and control symptoms of a DVT
  • learn more about whether treating a DVT in someone with advanced cancer is helpful

Who can enter

The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you. 

You may be able to join this study if all of the following apply. You

  • Have been admitted into a hospice  
  • Are able to have an ultrasound Open a glossary item
  • Are at least 18 years old

You cannot join this study if the study team feel it isn’t appropriate.

Trial design

The study team need 217 people to join. 

A nurse examines both of your legs for signs of a possible blood clot. They will also do an ultrasound of your legs using a bedside ultrasound scanner. This takes about 10 minutes.  

They do the examination and ultrasound weekly as long as you are in the hospice and you are happy for them to do it. 

Hospital visits

There are no hospital visits if you take part in this study. The ultrasound scans are done by the hospice nurse at your bedside.

Side effects

There are no side effects. 

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Miriam Johnson
Dr Clare White

Supported by

NIHR Research for Patient Benefit (RfPB) Programme
University of Hull

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Charlie took part in a trial to try new treatments

A picture of Charlie

“I think it’s really important that people keep signing up to these type of trials to push research forward.”

Last reviewed:

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