A study to increase the reliability and accuracy of MRI scanning in cancer (QuIBs)
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
Cancer type:
Status:
Phase:
This study is open to people who are outpatients of The Christie Hospital, Manchester. It is for people with one of the following cancers:
- liver cancer
- melanoma
- soft tissue sarcoma
- brain tumour
- head and neck cancer
- lung cancer
More about this trial
Doctors use magnetic resonance imaging scans (MRI) to diagnose cancer. They can also use them to see how well cancer is responding to treatment. As MRI scans become better they are used more often in treatment and clinical trials.
In this study researchers want to test new MRI imaging. And new ways to analyse the images which are being developed in Manchester. They want to try and increase understanding of how cancer cells grow and divide (cancer biology). In particular, the reliability of new techniques might depend on:
- the type of cancer
- where the cancer is in the body
- the new ways to get the information from the images
They will take MRI scans of people with different cancer types and look at the way the scan is done.
The researchers hope by doing this, they can work out the best way to scan. So that in the future people can have the most appropriate and reliable scan. Whether they are in a clinical trial or having treatment.
Who can enter
The following bullet points list the entry conditions for this study Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
You may be able to join this study if you are an outpatient at The Christie Hospital, Manchester and you have one of the following
And all of the following apply
- Your cancer is stable
- If you are to start treatment, it is a
standard treatment 
for your cancer - You are able to lie still comfortably for up to an hour
- You have satisfactory blood test results
- You are at least 18 years old
You cannot join this study if any of these apply. You
- Aren’t able to have an MRI scan. For example you have a pacemaker, metal plate or any other metal in your body
- Have asthma
- Are allergic to the contrast medium used or any of its ingredients
- Are pregnant or breastfeeding
Trial design
The researchers needs up to 450 people to join this study.
At one of your routine clinic appointments the doctor talks to you about the study. They give you an information sheet to take home and read. A few days later a member of the study team phones you to ask if you are interested in taking part.
As part of the study you have one or more MRI scans.
Before the scan the researcher might ask you to have an injection of a dye (a contrast medium). You don’t have to have the injection. You can still take part in the study.
Hospital visits
You have the MRI scan at the University of Manchester.
There are no extra hospital visits if you take part in the study.
Side effects
The side effects of the contrast medium are mostly mild. They include a metallic taste in the mouth and feeling sick.
We have information on MRI scans.
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Chief Investigator
Professor Alan Jackson
Supported by
Experimental Cancer Medicine Centre (ECMC)
University of Manchester
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
