A study to find out why certain people develop oesophageal cancer (ChOPIN)

There are several risk factors for oesophageal cancer. These include things such as lifestyle, the environment or genetic makeup .

This study collected blood samples and studied the DNA from people who have:

• reflux (also called erosive) oesophagitis
• Barrett’s oesophagus or
• oesophageal cancer 

Researchers have already identified some genes that may affect the risk of oesophageal cancer, but they wanted to learn more.

In this study, the researchers collected blood samples from people to help find out possible causes of oesophageal cancer that are related to their genes.

The aims of the study were to find out why:

• Some people develop Barrett’s oesophagus
• Some people with Barrett’s oesophagus then develop oesophageal cancer