A study to find out more about how cancer and the treatment affects everyday life (HORIZONS Study)

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Blood cancers
Breast cancer
Cervical cancer
Non-Hodgkin lymphoma
Ovarian cancer
Vulval cancer
Womb (uterine or endometrial) cancer





This study is for people recently diagnosed with certain cancers who are waiting to have treatment. The cancer types include:

More about this trial

A growing number of people are living for many years after cancer treatment. But we don’t yet know all the ways to support them to ensure the best possible recovery.

Understanding what is important to people with cancer during their treatment and in the months and years afterwards will help decide the type of support and services people need in the future. 

The aim of this study is to find out how a diagnosis of cancer and its treatment affects people in the short, medium and long term.

Who can enter

The following bullet points list the entry conditions for this study. Talk to your doctor or the hospital study team if you are unsure about any of these. They will be able to advise you. 

You might be able to join this study if you have been newly diagnosed with 1 of the following:

And all of the following apply. You:

  • Are due to have treatment with the aim of curing your cancer
  • Are able to write in English well
  • Are at least 16 years old - and under 50 years old if you have breast cancer

You cannot join this study if any of these apply. You

  • Have cancer that has come back or got worse in an area where you have  already had treatment
  • Have cancer that has spread to another part of the body
  • Have 2 or more different types of cancer (primary cancers) being looked at in the study that started to grow at the same time 

Trial design

This study is based in the UK. The researchers need 3,000 people to take part.

You fill in questionnaires before you start treatment and:

  • at 3 months
  • at 12 months
  • at 18 months 
  • at 2 years
  • once a year after that

The questionnaires ask about:

  • your health and wellbeing
  • any treatment you are having and how it affects you physically and emotionally – this is called your quality of life

You complete them on paper or online. The study team will also ask to look at your medical notes to find out more information about the treatment you are having.

Hospital visits

There are no extra hospital visits if you take part in this study. The questionnaires take about 45 minutes to complete.

Side effects

The study team do not expect there to be any risks or disadvantages from taking part in this study. 

They understand that joining the study comes at a time when you have a lot to deal with. Sometimes people find it hard difficult to talk or write about their experiences of having cancer. 

You don’t have to answer any questions in the questionnaire that you don’t want to.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Claire Foster

Supported by

Macmillan Cancer Support
University of Southampton
University Hospitals Southampton NHS Foundation Trust

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Over 60,000 cancer patients enrolled on clinical trials in the UK last year.

Last reviewed:

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