
“I think it’s really important that people keep signing up to these type of trials to push research forward.”
This study is looking at whether a special MRI scan of your brain can help to predict how well treatment will work.
It is for people with melanoma that has spread to the brain. And who are going to have an or a
.
One of the most common places melanoma can spread to is the brain.
Immunotherapy works well for about half of the people whose melanoma has spread to the brain. But immunotherapy can have serious side effects. This can happen even at the correct dose and with careful monitoring.
So researchers are looking for ways to predict who might benefit from immunotherapy before starting treatment. In this study they are using a special (DTI- MRI scan) of the brain to see if they can find out who might benefit or not.
To find this out the team need people with melanoma that has spread to the brain and who are about to start treatment with:
Please note you won’t get any direct benefit from taking part in this study. But in the future doctors could use this information to give more personalised treatment for people with melanoma that has spread.
The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this study if all of the following apply. You:
Who can’t take part
You cannot join this study if any of these apply. You:
This is a pilot study. The team need up to 20 people to join.
You have an MRI scan before starting treatment and once during treatment. Each scan takes about 15 minutes.
At the same time as the MRI scan the team take a blood sample.
The researchers will look at your medical records to find out:
You have both the MRI scans at The Walton Centre NHS Foundation Trust.
MRI scan is a safe procedure and the study team do not expect you to have any side effects from this scan.
We have information about:
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Rasheed Zakaria
Cancer Research UK
Royal College of Surgeons
The Walton Centre NHS Foundation Trust
University of Liverpool
The Clatterbridge Cancer Centre NHS Foundation Trust
Freephone 0808 800 4040
“I think it’s really important that people keep signing up to these type of trials to push research forward.”