A study to develop a screening test for bowel cancer (NIL)
Cancer type:
Status:
Phase:
This study is looking at using neurotensin and IL-8 to screen for bowel cancer and bowel 
.
It is open to people who are having a at Lancashire Teaching Hospitals.
More about this trial
The FIT test is a screening test for bowel cancer. This test looks for very small amounts of blood in your poo. If there are small amounts detected you might have a colonoscopy.
Your GP might also refer you to a specialist at the hospital if you have possible symptoms of bowel cancer. They do this through an urgent referral. The specialist will arrange for you to have tests. One test might be a colonoscopy.
Researchers think they can measure substances in the blood to find out if you might have:
- bowel cancer
- large bowel polyps.
These substances are neurotensin and I-L8.
They want to develop a test using these substances to screen for bowel cancer and large bowel polyps. And the researchers think this might be a better and quicker way to screen for bowel cancer.
The aims of this study are to develop a screening test and find out well it works.
Who can enter
The following bullet points are a summary of the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this study if you are to have a colonoscopy at Lancashire Teaching Hospitals.
Who can’t take part
You cannot join this study if any of these apply. You:
- need to have emergency surgery
- have an inflammatory bowel disease such as Crohn’s
- have had bowel cancer caused by an inherited condition such as
Lynch syndrome (HNPCC) or familial adenomatous polyposis (FAP - have had another cancer
- had cancer that has spread to the liver
- had a previous colonoscopy that showed there was no cancer
- have any other medical condition or mental health problem that could affect you taking part
Trial design
This is a . The team are applying for funding so they can increase the number of people able to join the study to 500.
When you have your colonoscopy the team take a blood sample. They give the sample a unique code so no one knows whose it is. They test the sample for the amounts of neurotensin and IL-8.
The team will also look at your medical records for information such as:
- your age
- your gender
- your height and weight
- any other medical conditions
Hospital visits
There are no extra visits if you take part in this study.
Side effects
There are no side effects from taking part in this study.
We have information on having a colonoscopy.
Location
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Chief Investigator
Mr Georgios Sgourakis
Supported by
Lancashire Teaching Hospitals NHS Trust
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
