“I was keen to go on a clinical trial. I wanted to try new cancer treatments and hopefully help future generations.”
A study of exercise for women with newly diagnosed breast cancer
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is looking at a new exercise programme for women who are due to have treatment for breast cancer.
The exercise programme involves cycling on a stationary bike. It is called reduced exertion high intensity interval training (REHIT).
More about this trial
Exercise can improve treatment outcomes, health and wellbeing for people with breast cancer. It is important to do exercise both before and after surgery. But it can be difficult to do the recommended 30 minutes of exercise a day. This may be due to not having enough time.
We know from research that shorter session cycling sprints can result in health benefits too. This is reduced exertion high intensity interval training (REHIT). The main advantage of this new type of exercise is that it only takes 10 minutes 3 times per week.
Researchers want to see if this type of exercise helps women having treatment for breast cancer. Some women do the REHIT exercise programme. And some continue with their usual levels of physical activity.
This study aims to find out if REHIT can improve the health and wellbeing of women with newly diagnosed breast cancer.
Who can enter
- have a recent diagnosis of invasive breast cancer
- are a woman
- can start the study within 1 week of diagnosis and before you have surgery
- have surgery arranged within 1 to 4 weeks of diagnosis
- have a treatment plan that includes surgery, followed by hormone treatment and/or radiotherapy and possibly chemotherapy
- are well enough to be up and about for at least half the day (performance status 0,1 or 2)
- are between 35 and 60 years of age
- have cancer that has spread elsewhere in the body
- are having chemotherapy before surgery
- are male
- are overweight (have a body mass index that is higher than 35)
- already do more than 5 exercise sessions per week that last longer than 30 minutes
- can’t do exercise for any reason
- have an autoimmune condition or arthritis that limits the exercise you can do
- have had any other cancer in the last 5 years apart from non melanoma skin cancer, very early skin cancer (CIS) or abnormal cells on the cervix
- have any serious heart, lung or any other medication condition that the study team think could affect you taking part
- the REHIT exercise group
- the usual levels of activity group (control group)
- give a blood sample
- have height and weight measurements
- complete quality of life questionnaires
- complete a short cycling fitness test
- complete a test to check your hand grip strength
- a short warm up
- 2 short cycle sprints
- a short warm down
- analyse blood sugar levels and levels of the hormone insulin
- look at levels of other substances related to health and long term disease including fatty acid and cholesterol
- blood samples
- height and weight measurements
- 3 testing sessions
- REHIT exercise sessions
- a final visit 7 weeks after surgery - the researchers will repeat the tests you had during the testing sessions
Your muscles may feel sore after exercise and the sessions may be tiring. But the exercise sprints are short, and the risk of injury is low.
How to join a clinical trial
Dr Niels Vollaard
University of Stirling