Cancer Research UK logo.
SearchDonate
  • Search

A study looking at a new biological therapy to treat chronic myeloid leukaemia

Overview

Cancer types:

Blood cancers, Chronic leukaemia, Chronic myeloid leukaemia (CML), Leukaemia

Status:

Closed

Phase:

Phase 2

Details

This study is to see how well nilotinib (Tasigna) works as a first treatment for chronic myeloid leukaemia (CML). Most people with chronic myeloid leukaemia (CML) have an abnormal called the Philadelphia chromosome. This develops if some DNA from one chromosome sticks to another when the cell divides, creating an abnormal gene called ‘bcr/abl’. Bcr/abl produces an called , which encourages leukaemia cells to grow and multiply.

Recruitment start: 1 December 2008

Recruitment end: 1 May 2011

How to join

Please note: In order to you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Michael O’Dwyer

Supported by

Experimental Cancer Medicine Centre (ECMC)

Cancer Trials Ireland

Novartis

Last reviewed: 11 Jul 2011

CRUK internal database number: 4379

Help and support