
“I think it’s really important that people keep signing up to these type of trials to push research forward.”
In this study researchers measure the amount of chemotherapy drugs in the blood. They want to see how different levels of the drugs affect how well they work and the side effects.
We know from previous research there are differences in how well people’s bodies get rid of chemotherapy drugs. It’s possible to measure the levels of chemotherapy in the blood from a blood sample. This tells doctors how well your body gets rid of the chemotherapy.
Knowing this can help the doctor adjust the dose of chemotherapy that some people need.
In this study researchers will use some of these blood samples and look at medical records. They want to find out if different levels of chemotherapy affect:
You may not get any benefit from joining the trial but the information gained might help people in in the future.
The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this study if all of the following apply.
The study team expect about 300 children, teenagers and young people to join this study.
As part of your care you have regular blood samples taken. They will take extra samples when you have blood tests as part of your usual care. They will send these samples to the Newcastle University Centre for Cancer for analysis. After this anything remaining of the sample is stored until the end of the study.
At the end of the study they will move these remaining blood samples to the Children’s Cancer and Leukaemia Group (GCLG) for use in future research. You don’t have to agree to this if you don’t want to. You can still take part in the study.
As part of the study the team will ask your doctor to send them your medical details before and after your treatment.
There are no extra hospital visits if you take part in the study.
The study team will continue to follow you through your medical records for 3 years.
There are no side effects if you take part in this study.
We have information about the side effects of chemotherapy.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Deborah Tweedle
National Institute for Health Research (NIHR)
Newcastle University
Freephone 0808 800 4040
“I think it’s really important that people keep signing up to these type of trials to push research forward.”