A study looking at scans to see how chemoradiotherapy is working for head and neck cancers

Cancer type:

Head and neck cancers





This study looked at a number of different scans to see how head and neck cancers responded to chemoradiotherapy Open a glossary item

The study was open for people to join between 2013 and 2016. The team published the results in 2018.

More about this trial

Doctors often treat head and neck cancers with a combination of radiotherapy and chemotherapy. This is called chemoradiotherapy. 

When this study was done, doctors used CT scans and MRI scans to see the size and shape of the cancer.

In this study, they used 4 other scans to find out more about the cancer. They were:

  • PET-CT scan
  • DW MRI scan
  • IS MRI scan
  • DCE MRI scan

The people taking part had scans before starting chemoradiotherapy, and during the first two weeks of treatment. The team then looked at the scan results, and how well treatment had worked for each person.

The main aim of this study was to find out if these scans can predict how well chemoradiotherapy will work for head and neck cancers.

Summary of results

As part of our editorial policy, any information we write is checked externally before we put it on our website. The research team have published some results for this study. But we have been unable to find anyone involved with the study to check the summary for us. 

This means we are not able to include a plain English summary of the results on this page.

More information
There is more information about this research in the reference below. 

Please note, the article we link to here is not in plain English. It has been written for health care professionals and researchers.

Changes in multimodality functional imaging parameters early during chemoradiation predict treatment response in patients with locally advanced head and neck cancer
Kee. H. Wong and others
European Journal of Nuclear Medicine and Molecular Imaging, 2018. Volume 45, Issue 5, pages 759 to 767.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr Kate Newbold

Supported by

NIHR Clinical Research Network: Cancer
The Royal Marsden NHS Foundation Trust

If you have questions about the trial please contact our cancer information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Last reviewed:

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