A study looking at quality of life of people with cancer (ECTQoL)

Cancer type:

Breast cancer





This study looked at how treatments affected the quality of life of people with cancer.

More about this trial

The National Institute for Health and Care Excellence (NICE) consider how a treatment affects quality of life Open a glossary item when deciding if it should be available to people in England and Wales. So it is important to have the best information possible.

Researchers wanted to identify a way of finding out how treatment affected a person’s quality of life. In this study, they asked people who had breast cancer to fill in questionnaires at their routine clinic hospital appointments. 

The aim of the study was to find out if it would be possible to do a large study looking at how cancer treatments affect quality of life.

Summary of results

The study team found that it was possible to collect information about peoples’ quality of life from routine clinic appointments at the hospital. 

This study recruited 79 people who were having treatment for breast cancer at Weston Park Hospital in Sheffield or Clatterbridge Cancer Centre in the Wirral. Most of the people the researchers asked to join the study did so. 

Of the 79 people who joined the study, 78 were having chemotherapy and 1 person was having hormone therapy.

Each person filled in a short questionnaire about how their cancer treatment had affected their quality of life. The questions asked if their treatment caused:

  • problems with walking about
  • problems with taking care of themselves
  • problems doing their daily activities
  • any pain or discomfort
  • anxiety or depression 

Doctors were also asked to fill in a short questionnaire about the stage of the disease, treatment offered and the response of the treatment.  

The study team concluded that it was possible to collect high quality information about quality of life from patients at routine clinical appointments.  

However, it was not possible for doctors to report accurately on the response of the treatment because additional diagnostic tests would need to be carried out and these were not routinely done. 

This was only a small study and the researchers couldn’t draw any firm conclusions about effects of treatments on quality of life. They stated that to do this, a study with a larger number of people was needed as well as additional diagnostic tests to determine how patients were responding to treatments.  

We have based this summary on information from the team who ran the trial.  As far as we are aware, the information they sent us has not been reviewed independently (peer reviewed Open a glossary item) or published in a medical journal yet. The figures we quote above were provided by the trial team. We have not analysed the data ourselves.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Simon Dixon

Supported by

Clatterbridge Cancer Centre NHS Foundation Trust
NIHR Clinical Research Network: Cancer
National Institute for Health and Care Excellence (NICE)
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

If you have questions about the trial please contact our cancer information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Last reviewed:

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